Comparison of Two Different Protocols for the Treatment of Acute Escherichia coli Mastitis in Dairy Cattle
DOI:
https://doi.org/10.6000/1927-520X.2017.06.02.1Keywords:
Dairy cow, E-coli, Mastitis, ceftiofurAbstract
E-coli mastitis is one of the most frequent causes of environmental mastitis in the dairy cattle worldwide. The purpose of this field study was to compare the efficacy of ceftiofur (HCL) in conjunction with supportive measures versus supportive measures alone for treatment of dairy cows affected with naturally occurring acute form of E. coli mastitis. From January 2014 to December 2016 a total number of 100 cows naturally affected by acute E-coli mastitis randomly were allocated into two groups. A milk sample from the affected quarter was collected for bacteriological tests on the first day of treatment. In group A (control), fifty cows received ceftiofur (HCL) 1mg/5kg/BW, flunixin meglumine 2.2mg/kg, calcium borogluconate 40%, 250ml and hypertonic saline (Nacl 7.2 %,) 5ml/kg. In group B (treatment, n=50), cows received the same drugs mentioned for group A, except ceftiofur (HCL) which replaced by placebo. In the group A, 41cows (82%) and in the group B, 2 cows (4%) were survived respectively. The rates of quarter health recovery in the groups A and B were 31.7% and 0% respectively. The differences between two groups were significant (P≤0.01).
In conclusion our results indicated that treatment of cows affected with naturally occurring acute form of E. coli mastitis without application of effective antibiotic(s) such as ceftiofur (HCL) and fluid therapy almost impossible.
References
Katholm J, Andersen PH. Acute coliform mastitis in dairy cows: Endotoxin and biochemical changes in plasma and colony-forming units in milk. Vet Rec 1992; 131: 513-514. https://doi.org/10.1136/vr.131.22.513 DOI: https://doi.org/10.1136/vr.131.22.513
Persson Y, Katholm J, Landin H, Mörk MJ. Efficacy of enrofloxacin for the treatment of acute clinical mastitis caused by Escherichia coli in dairy cows. Vet Rec 2015; 176: 673. https://doi.org/10.1136/vr.102667 DOI: https://doi.org/10.1136/vr.102667
Blowey R, Edmondson P. Mastitis control in dairy herds. 2 ed. Cambridge, MA: CAB International 2010. https://doi.org/10.1079/9781845935504.0000 DOI: https://doi.org/10.1079/9781845935504.0000
Anderson, K.L. Therapy for acute coliform mastitis. CompendContinEduc Vet 1989; 11: 1125-1133.
Hoeben D, Burvenich C, Trevisi E, Bertoni G, Hamann J, Bruckmaier RM, Blum JW. Role of endotoxin and TNF-alpha in the pathogenesis of experimentally induced coliform
mastitis in periparturient cows. J Dairy Res 2000; 67: 503-514. https://doi.org/10.1017/S0022029900004489 DOI: https://doi.org/10.1017/S0022029900004489
Lee JW, Paape MJ, Elsasser TH, Zhao X. Recombinant soluble CD14 reduces severity of intramammary infection by Escherichia coli. Infect Immun 2003; 71: 4034-4039. https://doi.org/10.1128/IAI.71.7.4034-4039.2003 DOI: https://doi.org/10.1128/IAI.71.7.4034-4039.2003
Shuster DE, Lee EK, Kehrli ME Jr. Bacterial growth, inflammatory cytokine production, and neutrophil recruitment during coliform mastitis in cows within ten days after calving, compared with cows at midlactation. Am J Vet Res 1996; 57: 1569-1575. DOI: https://doi.org/10.2460/ajvr.1996.57.11.1569
Vangroenweghe F, Duchateau L, Burvenich C. Moderate inflammatory reaction during experimental Escherichia coli mastitis in primiparous cows. J Dairy Sci 2004; 87: 886-895. https://doi.org/10.3168/jds.S0022-0302(04)73233-6 DOI: https://doi.org/10.3168/jds.S0022-0302(04)73233-6
Van Oostveldt K, Tomita GM, Paape MJ, Capuco AV, Burvenich C. Apoptosis of bovine neutrophils during mastitis experimentally induced with Escherichia coli or endotoxin. Am J Vet Res 2002; 63: 448-453. https://doi.org/10.2460/ajvr.2002.63.448 DOI: https://doi.org/10.2460/ajvr.2002.63.448
Hagiwara S, Mori K, Okada H, Oikawa S, Nagahata H. Acute Escherichia coli Mastitis in Dairy Cattle: Diagnostic Parameters Associated with Poor Prognosis. J Vet Med Sci 2014; 76(11): 1431-1436. https://doi.org/10.1292/jvms.13-0610 DOI: https://doi.org/10.1292/jvms.13-0610
Pyörälä S. Treatment of mastitis during lactation. Ir Vet J 2009; 62: S40. https://doi.org/10.1186/2046-0481-62-S4-S40 DOI: https://doi.org/10.1186/2046-0481-62-S4-S40
Hogan JS, Smith KL. Coliform mastitis. Vet Res 2003; 34: 507-519. https://doi.org/10.1051/vetres:2003022 DOI: https://doi.org/10.1051/vetres:2003022
Cebra CK, Garry FB, Dinsmore RP. Naturally occurringacute coliform mastitis in Holstein cattle. J Vet Intern Med 1996; 10: 252-257. https://doi.org/10.1111/j.1939-1676.1996.tb02058.x DOI: https://doi.org/10.1111/j.1939-1676.1996.tb02058.x
Wenz JR, Barrington GM, Garry FB, McSweeney KD, Dinsmore RP, Goodell G, Callan RJ. Bacteremia associated with naturally occurring acute coliform mastitis in dairy cows. J Am Vet Med Assoc 2001; 219: 976-981. https://doi.org/10.2460/javma.2001.219.976 DOI: https://doi.org/10.2460/javma.2001.219.976
Middleton JR, Saeman A, Fox LK, Lombard J, Hogan JS, Smith KL. The National Mastitis Council: A Global Organization for Mastitis Control and Milk Quality, 50 Years and Beyond. J Mammary Gland Biol Neoplasia 2014; 19: 241-251. https://doi.org/10.1007/s10911-014-9328-6 DOI: https://doi.org/10.1007/s10911-014-9328-6
Suojala L, Kaartinen L, Pyörälä, S. Treatment for bovine Escherichia coli mastitis - an evidence-based approach. J Vet Pharmacol Therap 2013; 6: 521-31. https://doi.org/10.1111/jvp.12057 DOI: https://doi.org/10.1111/jvp.12057
Bargi A, Hamali H, Nofouzi K, Saberivand A, Johari- Ahar S. Effect of intravenous infusion of hypertonic saline on treatment of the cows with acute E. coli mastitis. Bull Env Pharmacol Life Sci 2015; 4(3): 01-04.
Erskine RJ, Bartlett PC, VanLente JL, Phipps CR. Efficacy of Systemic Ceftiofur as a Therapy for Severe Clinical Mastitis in Dairy Cattle. J Dairy Sci 2002; 85(10): 2571-2575. https://doi.org/10.3168/jds.S0022-0302(02)74340-3 DOI: https://doi.org/10.3168/jds.S0022-0302(02)74340-3
Truchetti G, Bouchard E, Descôteaux L, Scholl D, Roy JP. Efficacy of extended intramammary ceftiofur therapy against mild to moderate clinical mastitis in Holstein dairy cows: A randomized clinical trial. Can J Vet Res 2014; 78(1): 31-37.
Morin DE, Shanks RD, McCoy GC. Comparison of antibiotic administration in conjunction with supportive measures versus supportive measures alone for treatment of dairy cows with clinical mastitis. J Am Vet Med Assoc1998; 213(5): 676-84. DOI: https://doi.org/10.2460/javma.1998.213.05.676
Katholm J. Treatment of Coliform Mastitis in Bovine Practice: - Can Antibiotics be avoided? Acta Veterinaria Scandinavica 2003; 44(1): 8. https://doi.org/10.1186/1751-0147-44-S1-P8 DOI: https://doi.org/10.1186/1751-0147-44-S1-P8
Ward WR, Hughes JW, Faull WB, Cripps PJ, Sutherland JP, Sutherst JE. Observational study of temperature, moisture, pH and bacteria in straw bedding, and faecal consistency, cleanliness and mastitis in cows in four dairy herds. Vet Rec 2002; 151(7): 199-206. https://doi.org/10.1136/vr.151.7.199 DOI: https://doi.org/10.1136/vr.151.7.199
Hogan, J, Weiss, W, Todhunter, D, Smith, K, Schoenberger, P. Efficacy of an Escherichia coli J5 mastitis vaccine in an experimental challenge trial. J Dairy Sci 1992; 75(2): 415-422. https://doi.org/10.3168/jds.S0022-0302(92)77777-7 DOI: https://doi.org/10.3168/jds.S0022-0302(92)77777-7
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