Amount of Zinc Transferred in Breast Milk to Breastfed Moroccan Babies with Normal or Low Birth Weight at 1, 3 and 6 Months After Birth

Authors

  • Ghizlane choua Unité Mixte de Recherche en Nutrition et Alimentation, (Université Ibn Tofail-CNSTEN), URAC 39, Rabat, Morocco
  • Nourddine EL HALOUI Unité Mixte de Recherche en Nutrition et Alimentation, (Université Ibn Tofail-CNSTEN), URAC 39, Rabat, Morocco
  • Khalid EL KARI Unité Mixte de Recherche en Nutrition et Alimentation, (Université Ibn Tofail-CNSTEN), URAC 39, Rabat, Morocco
  • Hassan AGUENAOU Unité Mixte de Recherche en Nutrition et Alimentation, (Université Ibn Tofail-CNSTEN), URAC 39, Rabat, Morocco
  • Najat MOKHTAR International Atomic Energy Agency, Vienna International Centre, Vienna, Austria

DOI:

https://doi.org/10.6000/1929-4247.2014.03.01.6

Keywords:

Zinc in breastmilk, LBW, Exclusive breastfeeding, Model of zinc concentration

Abstract

The amount of zinc in breast milk is generally regarded as sufficient to cover the increasing zinc demands of most infants. However, this is not well investigated where stores zinc may be compromised in babies with low birth weight (LBW) who are born with low stores of zinc. In Morocco, this is the first time that the amount of zinc transferred in breast milk has been estimated. This study included 32 mother-baby pairs. In our case study, we aimed to measure The quantity of zinc in mothers’ breast milk with normal birth weight (NBW) and LBW babies who were exclusively or not exclusively breast fed at 1,3 and 6 month after birth. The results showed that the majority of mothers have a BMI ≥25 kg/m2 this means that all mothers are overweight during 6 months after birth. Zinc concentration (mg/l) in mothers’ breast milk decreased from first month to six month. p- value showed that for mothers with NBW babies, there is a significant difference between the 1 and 6 month (p=0.0003) and between 3 and 6 month after birth (p=0.0007). For mothers with LBW babies, p-value showed a significant difference between the zinc concentration in breast milk in the 1st and 3rd month (p=0.0007), 1 and 6 month (p< 0.0001) and between 3rd and 6th month after birth (p=0.0056). The rate of NBW babies who were exclusively breastfed was 36.67%, 30.25% and 10% successively in 1st, 3rd and 6th month after birth. For LBW babies, the rate of exclusively breastfed was 15.38%, 7.69% and 2.69% successively in 1st, 3rd and 6th month after birth. Based on the K. Brown study in 2009, we can develop a mathematical equation to our own population using our data: Ln [Zinc] = 0.960 – 0.161*Ln(âge) – 0.187*Ln(âge)2. In conclusion the zinc concentration in milk is within normal range and decreases with the age of the babies. The predicted model of zinc concentration in breast milk was developed and tested.

References

Brown KH, Rivera JA, Bhutta Z, Gibson RS, King JC, Lönnerdal B, et al. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr Bull 2004; 25(1 suppl 2): S99-203.

de Benoist B, Darnton-Hill I, Davidsson L, Fontaine O, Hotz C. Conclusions of the joint WHO/UNICEF/IAEA/IZiNCG interagency meeting on zinc status indicators. Food Nutr Bull 2007; 28: S480-S79.

Hess SY, Brown K. Impact of zinc fortification on zinc nutrition. Food Nutr Bull 2009; March.

Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, et al. Maternal and child undernutrition: Global and regional exposures and health consequences. Lancet 2008; 371: 243-60. http://dx.doi.org/10.1016/S0140-6736(07)61690-0

Bahl L, Chaudhuri LS, Pathak RM. Study of serum zinc in neonates and their mothers in Shimla hills (Himachal Pradesh). Indian J Pediatr 1994; 61: 571-5. http://dx.doi.org/10.1007/BF02751721

Nakamori M, Ninh NX, et al. Nutritional Status of Lactatting Mothers and Their Breast Milk Concentration of Iron, Zinc and Copper in Rural Vietnam. J Nutr Sci Vitaminol 2009; 55: 338-45. http://dx.doi.org/10.3177/jnsv.55.338

WHO. Complementary feeding of young children in developing countries: a review of current scientific knowledge. Geneva, World Health Organization 1998.

Lamounier JA, Danelluzzi JC, Vannucchi H. Zinc concentrations in human milk during lactation: a 6-month longitudinal study in southern Brazil. J Trop Pediatr 1989; 35: 31-4. http://dx.doi.org/10.1093/tropej/35.1.31

Choua G. EL Kari K, EL Haloui N, Slater C, Aguenaou H. Mokhtar N. Quantitative assessment of breastfeeding practices and maternal body composition in Moroccan lactating women during six months after birth using stable isotopic dilution technique. Int J Mater Child Health 2013; 1(3): 45-50. DOI: 10.12966/ijmch.09.01.2013.

Brown KH, Engle-Stone R, Krebs NF, Peerson JM. Dietary intervention strategies to enhance zinc nutrition: Promotion and support of breastfeeding for infants and young children. Food and Nutrition Bulletin, vol. 30, no. 1 (supplement) © 2009, The United Nations University.

Elizabeth KE, Krishnan V, Vijayakumar T. Umbilical cord blood nutrients in low birth weight babies in relation to birth weight and gestational age. Indian J Med Res 2008; 128: 128-33.

Sellen DW. Evolution of Infant and Young Child Feeding: Implications for Contemporary Public Health. Ann Rev Nutr 2007; 27: 123-48. http://dx.doi.org/10.1146/annurev.nutr.25.050304.092557

Piletz JE. Ganschow REIs acroderrnatitis enteropathica related to the absence of zinc binding ligand in bovine milk? Am J Clin Nutr 1979; 32(2): 275-77.

WHO. Global strategy for infant and young child feeding. WHO Library Cataloguing-in-Publication Data, Geneva 2003.

Enquête Nationale à Indicateurs Multiples et Santé des Jeunes: ENIMSJ 2006-2007, 2008. Maroc. http://srvweb. sante.gov.ma/Publications/Etudes_enquete/Documents/ENIMSJ_%20Rapport%20final.pdf

Senarath U, Dibley MJ, Agho KE. Factors Associated With Nonexclusive Breastfeeding in Five East and Southeast Asian Countries: A Multilevel Analysis. J Hum Lact 2010; 26(3): 248-57. http://dx.doi.org/10.1177/0890334409357562

WHO. The world health report 2000 - Health systems: improving performance. ISBN 92 4 156198 X. France 2000.

Brown KH, Dewey KG, Allen LH. Complementary feeding of young children in developing countries: A review of current scientific knowledge. Geneva: World Health Organization 1998.

Hemalatha P, Bhaskaram P, Kumar PA, Khan MM, Islam MA. Zinc status of breastfed and formula-fed infants of different gestational ages. J Trop Pediatr 1997; 43: 52-4. http://dx.doi.org/10.1093/tropej/43.1.52

Higashi A, Ikeda T, Uehara I, Matsuda I. Zinc and copper contents in breast milk of Japanese women. Tohoku J Exp Med 1982; 137: 41-7. http://dx.doi.org/10.1620/tjem.137.41

Moser PB, Reynolds RD. Dietary zinc intake and zinc concentrations of plasma, erythrocytes, and breast milk in antepartum and postpartum lactating and nonlactating women: A longitudinal study. Am J Clin Nutr 1983; 38: 101-8.

Leotsinidis M, Alexopoulos A, Kostopoulou-Farri E. Toxic and essential elements in human milk from Greek lactating women. Association with dietary habits and other factors. Chemosphere 2005; 61: 238-47. http://dx.doi.org/10.1016/j.chemosphere.2005.01.084

Krebs NF, Reidinger CJ, Hartley S, Robertson AD, Hambidge KM. Zinc supplementation during lactation: Effects on maternal status and milk zinc concentrations. Am J Clin Nutr 1995; 61: 1030-6.

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Published

2014-03-10

How to Cite

choua, G., HALOUI, N. E., KARI, K. E., AGUENAOU, H., & MOKHTAR, N. (2014). Amount of Zinc Transferred in Breast Milk to Breastfed Moroccan Babies with Normal or Low Birth Weight at 1, 3 and 6 Months After Birth. International Journal of Child Health and Nutrition, 3(1), 48–54. https://doi.org/10.6000/1929-4247.2014.03.01.6

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General Articles