Anti-Inflammatory Activity of the Fruit Extract of Benincasa hispida

Authors

  • Deepak Kadam Food Engineering and Technology Department, Institute of Chemical Technology, N. P. Marg, Matunga, Mumbai 400019, India
  • Smita Lele Food Engineering and Technology Department, Institute of Chemical Technology, N. P. Marg, Matunga, Mumbai 400019, India

DOI:

https://doi.org/10.6000/1929-5634.2014.03.04.6

Keywords:

Benincasa hispida, Phytochemicals, Anti-inflammatory, HRBC membrane stabilization, Carrageenan.

Abstract

Benincasa hispida (Ash gourd, family: Cucurbitaceae) is well known for its medicinal property. In the Ayurvedic system, it is used as a rejuvenating agent and in the treatment of nervous disorders. Methanolic and petroleum fruit extracts was subjected to evaluation of phytochemicals and acute oral toxicity study. Further, Anti-inflammatory activity was performed using human red blood cell (HRBC) membrane stabilization assay and carrageenan induced paw edema in rat. Oral administration of methanolic extract of concentration (350 mg/kg) significantly reduced the paw edema (P < 0.05) in a dose dependent manner as compared to carrageenan induced rats.

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Published

2014-12-22

How to Cite

Kadam, D., & Lele, S. (2014). Anti-Inflammatory Activity of the Fruit Extract of Benincasa hispida. Journal of Nutritional Therapeutics, 3(4), 178–182. https://doi.org/10.6000/1929-5634.2014.03.04.6

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