Production of Cysteine: Approaches, Challenges and Potential Solution

Authors

  • Nur Izzah Ismail International Islamic University Malaysia
  • Yumi Zuhanis Has-Yun Hashim International Islamic University Malaysia
  • Parveen Jamal International Islamic University Malaysia
  • Rashidi Othman International Islamic University Malaysia,
  • Hamzah Mohd Salleh International Islamic University Malaysia

DOI:

https://doi.org/10.6000/1927-3037.2014.03.03.3

Keywords:

Amino acid biosynthesis, cysteine production, cysteine purification, sulfur amino acid.

Abstract

Cysteine has a wide application in pharmaceutical, foods and cosmetic industries. In the biological system, through its unique properties of sulfur and thiol, cysteine also plays important roles in stability, structure, catalytic activity, and regulation of numerous proteins. In nature, cysteine can be found in animal proteins, fruits, vegetables, legumes and cereal. Due to its wide application, the production of cysteine in large scale is in favour. At present, cysteine is produced from keratin of animal sources as well as through microbial bioconversion and fermentation. Each production method poses its own challenges and limitation; which includes low yield, high-cost and poor consumer acceptance. As such, alternative source for large-scale cysteine production is of interest. Plants are seen to be an attractive substrate for the extraction of cysteine.

Author Biographies

Nur Izzah Ismail, International Islamic University Malaysia

Biotechnology Engineering

Yumi Zuhanis Has-Yun Hashim, International Islamic University Malaysia

Biotechnology Engineering

Parveen Jamal, International Islamic University Malaysia

Biotechnology Engineering

Rashidi Othman, International Islamic University Malaysia,

Landscape Architecture

Hamzah Mohd Salleh, International Islamic University Malaysia

Biotechnology Engineering

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Published

2014-10-15

Issue

Section

Articles