Production of Cysteine: Approaches, Challenges and Potential Solution

Authors

  • Nur Izzah Ismail Bioprocess and Molecular Engineering Research Unit (BPMERU), Department of Biotechnology Engineering, Kulliyyah of Engineering, International Islamic University Malaysia, P.O. BOX 10, Kuala Lumpur, 50728, Malaysia
  • Yumi Zuhanis Has-Yun Hashim Bioprocess and Molecular Engineering Research Unit (BPMERU), Department of Biotechnology Engineering, Kulliyyah of Engineering, International Islamic University Malaysia, P.O. BOX 10, Kuala Lumpur, 50728, Malaysia
  • Parveen Jamal Institute for Halal Research and Training (INHART), E52-2 Level 2 Block E5, Kulliyyah of Engineering, International Islamic University Malaysia, P.O. Box 10, 50728, Kuala Lumpur, Malaysia
  • Rashidi Othman Department of Landscape Architecture, Kulliyyah of Architecture and Environmental Design, International Islamic University Malaysia, P.O. BOX 10, Kuala Lumpur, 50728, Malaysia
  • Hamzah Mohd Salleh Bioprocess and Molecular Engineering Research Unit (BPMERU), Department of Biotechnology Engineering, Kulliyyah of Engineering, International Islamic University Malaysia, P.O. BOX 10, Kuala Lumpur, 50728, Malaysia

DOI:

https://doi.org/10.6000/1927-3037.2014.03.03.3

Keywords:

Amino acid biosynthesis, cysteine production, cysteine purification, sulfur amino acid.

Abstract

Cysteine has a wide application in pharmaceutical, foods and cosmetic industries. In the biological system, through its unique properties of sulfur and thiol, cysteine also plays important roles in stability, structure, catalytic activity, and regulation of numerous proteins. In nature, cysteine can be found in animal proteins, fruits, vegetables, legumes and cereal. Due to its wide application, the production of cysteine in large scale is in favour. At present, cysteine is produced from keratin of animal sources as well as through microbial bioconversion and fermentation. Each production method poses its own challenges and limitation; which includes low yield, high-cost and poor consumer acceptance. As such, alternative source for large-scale cysteine production is of interest. Plants are seen to be an attractive substrate for the extraction of cysteine.

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Published

2014-10-15

How to Cite

Ismail, N. I., Hashim, Y. Z. H.-Y., Jamal, P., Othman, R., & Salleh, H. M. (2014). Production of Cysteine: Approaches, Challenges and Potential Solution. International Journal of Biotechnology for Wellness Industries, 3(3), 95–101. https://doi.org/10.6000/1927-3037.2014.03.03.3

Issue

Vol. 3 No. 3 (2014)

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