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journal-basic-applied-scien

Schiff Bases: Multipurpose Pharmacophores with Extensive Biological Applications - Pages 217-229

Khurram Shahzad Munawar, Shah Muhammad Haroon, Syed Ammar Hussain and Hamid Raza

https://doi.org/10.6000/1927-5129.2018.14.34

Published: 22 June 2018

Abstract: Schiff bases are substances prepared generally by the condensation reaction of aldehydes or ketones with amines. They may have substituted aliphatic or aromatic side chains, and hence show extensive biological activities. It is reported that these molecules play an important role in the synthesis of various drugs. This paper focus on the biological activities of Schiff bases of various types and hence makes them important precursors in designing drugs for medical treatment. The biological applications of Schiff bases can be extended from antimicrobial, plant growth regulator, antioxidant, enzymatic, anticancer, anti-inflammatory, anti-malarial, antiviral, neuroprotective, analgesic, anti-convulsant to neurotoxic activities. They also serve as a dominant class of ligands with a variety of binding sites for coordination with metals.

Keywords: Schiff bases, anti-microbial, anticancer, antiviral, antioxidant, anti-malarial.

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journal-basic-applied-scien

The Gauß Sum and its Applications to Number Theory - Pages 230-234

Nadia Khan, Shin-Ichi Katayama, Toru Nakahara and Hiroshi Sekiguchi

https://doi.org/10.6000/1927-5129.2018.14.35

Published: 22 June 2018

Abstract: The purpose of this article is to determine the monogenity of families of certain biquadratic fields K and cyclic bicubic fields L obtained by composition of the quadratic field of conductor 5 and the simplest cubic fields over the field Q of rational numbers applying cubic Gauß sums. The monogenic biquartic fields K are constructed without using the integral bases. It is found that all the bicubic fields L over the simplest cubic fields are non-monogenic except for the conductors 7 and 9. Each of the proof is obtained by the evaluation of the partial differents x-xr of the different F/Q (x) with F=K or L of a candidate number x, which will or would generate a power integral basis of the fields F. Here r denotes a suitable Galois action of the abelian extensions F/Q and F/Q (x) is defined by ÕreG\{i} (x-x)r, where G and i denote respectively the Galois group of F/Q  and the identity embedding of F.

Keywords: Monogenity, Biquadratic field, Simplest cubic field, Cyclic sextic field, Discriminant, Integral basis.

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Review of Pharmacological Activities of Vetiveria zizanoide (Linn) Nash - Pages 235-238

Saroosh Zahoor, Sammia Shahid and Urooj Fatima

https://doi.org/10.6000/1927-5129.2018.14.36

Published: 22 June 2018

Abstract: Vetiveria zizanioides (Linn) Nash is a perennial magical grass of family poaceae commonly known as Khas which is highly valued grass due to its adventitious root system. It is widely distributed in the Pakistan. It is cultivated in all provinces of Pakistan due to its great economic importance. This grass grows plain ascending up to 1200m. Mostly roots stem and leaves were used for treatment of different diseases by ancestors. Adventitious roots contain essential oil which used for multipurpose such as perfumery and in pharmacological industry. Vetiver oil contains approximately 150 compounds, including sesquiterpenoide, hydrocarbons. Phytochemical analysis of leaves shows the presence of flavonoides, saponins, tannins and phenols. Various tribes of India used this tuft grass for commercial purposes. Khas serve as broom, for cooling, roof of huts and as medicine for different diseases such as sunstroke, ulcer, fever, epilepsy and in skin diseases. In this study we summaries the magical pharmacological activities of Vetiveria zizanioides such as anti inflammatory, antibacterial, antifungal, and anti malarial, anti tubercular, anti hyperglycemic, anti hepatoprotective and antioxidant activity.

Keywords: Pharmacological activities, Khas, perfume, traditional medicine, biodiversity.

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journal-basic-applied-scien

Edge Version of Harmonic Index and Harmonic Polynomial of Rooted Product Graphs - Pages 239-245

Muhammad Shoaib Sardar, Rabia Nazir, Sohail Zafar and Zohaib Zahid

https://doi.org/10.6000/1927-5129.2018.14.37

Published: 22 June 2018

Abstract: In this paper we computed explicit formulas for the edge version of harmonic index and harmonic polynomial of some classes of rooted product of graphs and i-th vertex rooted product of graphs.

Keywords: Topological indices, line graph, harmonic index and harmonic Polynomial.

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