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Abstract: The analysis of aspartame was done in table top sweeteners using Ultraviolet visible Spectroscopy. The method is based on the formation of manganate ion (MnO42-) when potassium permanganate oxidizes aspartame. The analysis was carried out at a fixed wavelength of 600nm exactly after 48 minutes of sample preparation using 1mL of 0.01M KMnO4 and 2mL of 1.0M NaOH. A linear calibration graph was obtained with the regression coefficient of 0.9999 and the percentage recovery was in the range of 92.7-101.6%. The Relative standard deviation for the method was found to be 1.03%. Keywords: Aspartame, UV/Visible spectroscopy, Sweetener, KMnO4. Download Full Article |
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Abstract: Uncertainties in human health risk assessment, and the measuring on the impacts of contaminants have attracted great concern. Uncertainties, source-to-outcome, exposure assessment, hazard and risk characterisations are a number of techniques that have been applied to maximize results. Experts’ opinions and quantitative tools have been applied to narrow the gap between data and rules for regulatory purposes. Bio monitoring information,in vitrodata streams and computational toxicology are major areas for human health risk assessment. A need for a biomarkers data bank is of utmost need to minimize uncertainties in the toxicological environmental human health risk assessment field. Keywords: Aflatoxins, Exposure, Susceptibility, Effects, Monitoring, Contaminants. Download Full Article |
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Abstract: Carica papaya is a tropical fruit, present in orange red to yellow orange color. The whole plant including fruit, leaves, roots, peel, bark, seed and pulp served as medicine. It is rich in minerals, carotenoids, vitamins, alkaloids, enzymes, lycopene, and flavonoids that provide the papaya with special importance. It is used as a remedy for the treatment of many skin infections, anti fungal, anti viral infections. Its milky juice extracted and dried is used as medicine for digestive disorders and as toothpaste. Carica papaya helps in the treatment of different types of cancer, kidney infections, nervous disorders, etc. Now a days papaya is known as a nutraceutical fruit because of its multifaceted properties. The most enhanced properties of papaya are anti-fungal, anti-fertility, uretonic, anti-hypertensive, hypolipidemic, dengue fever, diuretic, anti-helmintic, wound healing, antibacterial and antitumor activities. This review summarizes the magical pharmacological benefits of Carica papaya. Keywords: Carica Papaya, Papain, Wound healing, Chymopapain, Neutraceutical. Download Full Article |
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Abstract: Lansium domesticum belongs to the family Meliaceae and is admired for its fruit in southern Asia. The family Meliaceae is known as novel bioactive compounds that are usually used in folk remedy as a drug for the treatment of diarrhea. The leaf and bark mixture of L. domesticum cv. duku exhibited antibacterial activity towards Bacillus subtile, Staphylococcus aureus, and Echerichia coli. Phytochemical screening of fruit waste of L. domesticum showed the presence of 3β -hydroxyonocera-8, 21α -hydroxyonocera-8, 14-dien-21-one and 14-dien-3-one, lansic acid. The seeds contain tetranortriterpenoids. The bark contains active compounds namely onoceradienedione, lansiolic acid A, iso-onoceratriene and 3-keto lansiolic acid. The methanolic extract of the bark of L. domesticum cv kokossan showed major antibacterial efficacy against Escherichia coli and. Bacillus subtilis The ethyl acetate extract exhibited an antibacterial efficacy with an inhibit zone respectively of 14 and 12.5 mm towards E. coli and B. cereus. Silver nanoparticles have a future in an antimicrobial role. The silver nanoparticles of L. domesticum are spherical in shape with a size from10-30 nm. Keywords: Meliaceae, Lansium domesticum, bioactive compounds, antibacterial efficacy. Download Full Article |
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Abstract: Schiff bases are substances prepared generally by the condensation reaction of aldehydes or ketones with amines. They may have substituted aliphatic or aromatic side chains, and hence show extensive biological activities. It is reported that these molecules play an important role in the synthesis of various drugs. This paper focus on the biological activities of Schiff bases of various types and hence makes them important precursors in designing drugs for medical treatment. The biological applications of Schiff bases can be extended from antimicrobial, plant growth regulator, antioxidant, enzymatic, anticancer, anti-inflammatory, anti-malarial, antiviral, neuroprotective, analgesic, anti-convulsant to neurotoxic activities. They also serve as a dominant class of ligands with a variety of binding sites for coordination with metals. Keywords: Schiff bases, anti-microbial, anticancer, antiviral, antioxidant, anti-malarial. Download Full Article |