Prof. Zhe-Sheng (Jason) Chen received his M.D. degree from Guangdong Medical and Pharmaceutical College (now, named as Guangdong Pharmaceutical University), Master degree from Sun Yat-Sen University School of Public Health, China and Ph.D. degree from Kagoshima University Faculty of Medicine, Japan. He worked as a JSPS (Japanese Society for Promotion Science) fellow in Japan and a postdoctoral fellow in medical oncology at Fox Chase Cancer Center. Currently Dr. Chen is a Professor at St. John’s University College of Pharmacy and Health Sciences. Dr. Chen is also a director of Institute for Biotechnology at St. John’s University. His interests range from laboratory studies and clinical studies on drug resistance in leukemia, ovarian cancer, lung cancer and others. His Cancer Pharmacology laboratory is dedicated to find anticancer agents that, alone, or in combination with other agents to circumvent drug resistance in cancer treatment.

Dr. Chen is also an Editor-in-Chief of Journal of New Developments in Chemistry, an editor of African Journal of Pharmacy and Pharmacology and an associate editor of Journal of Analytical Oncology, Journal of Cancer Metastasis and Treatment and a guest editor of Current Pharmaceutical Biotechnology. Dr. Chen is an editorial board member of 26 journals and a reviewer of more than 170 peer reviewed journals. As a consultant to pharmaceutical, biotechnology and health industry organizations, Dr. Chen commands more than 150 invitations for presentations, keynote addresses, and conference chairman. He published more than 180 publications in peer reviewed journals. Dr. Chen is also a grant reviewer of NIH (USA), Chinese National Natural Science Foundation (China), The Genesis Oncology Trust (New Zealand), National Science Centre (Poland), The Government of the Hong Kong Special Administrative Region (HKSAR) Grant, Hong Kong (China), the Hungarian Scientific Research Fund (OTKA) (Hungary), the Netherlands Organisation for Scientific Research (NWO) (Netherlands), the Czech Science Foundation (Czech) and The Ministry of Education and Science of the Russian Federal etc.

Editor-in-Chief:

Zhe-Sheng Chen  (St. John's University,  New York, NY, USA)  View Editor's Profile

Deputy Editors:

Suresh V. Ambudkar (NCI, NIH, Bethesda, MD, USA)

Senior Editor:

Liwu Fu (Sun Yat-Sen University Cancer Center, Guangzhou, China)

Senior Editorial Advisors:

Shin-Ichi Akiyama (Kyushu Cancer Center, Fukuoka, Japan)

Leonard Amaral (Institute of Hygiene & Tropical Medicine, Universidade Nova de Lisboa, Lisbon, Portugal and; Institute of Medical Microbiology and Immunology, University of Szeged, Szeged, Hungary)

Maria Baer (University of Maryland Medical Center, MD, USA)

Vladan Bajic (Institute for Nuclear Research ''Vinca'', Belgrade, Serbia)

Meiwan Chen (University of Macau, Macau)

Xiang Chen (Central South University, Changsha, China)

William C.S. Cho (Queen Elizabeth Hospital, Hong Kong)

Micheal Dean (National Cancer Institute, Frederick, MD, USA)

Ali El-Shekeil (Sana'a University, Sana'a, Yemen)

Shamil Kh. Gantsev (Baskhir State Medical University, Ufa, Russian Federation)

Ruo-Pan Huang (RayBiotech, Inc., Norcross, GA, USA)

Se-Kwon Kim (Marine Bioprocess Research Center Pukyong National University, Busan, South Korea)

Thomas Litman (LEO Pharma A/S, Denmark)

Jun (Jeremy) Long (University of Miami)

Jingxuan Pan (Sun Yat-sen University, Guangzhou, China)

Gary Piazza (University of South Alabama, Alabama, USA)

Marc Symons (The Feinstein Institute for Medical Research at North Shore-LIJ, Manhasset, NY, USA)

Diaa Youssef (King Abdulaziz University, Jeddah, KSA)

Yi-Xin Zeng (Sun Yat-Sen University, Guangzhou, China)

Wang Zhenling (The Key Laboratory of Rare Functional Materials and Applications, Zhoukou Normal University, Zhoukou, China)

Shu-Feng Zhou (University of South Florida (USF), Florida, USA)

Editorial Board Members:

Khalid Dafaallah Awadelkarim Abuelgasim (University of Gezira, Wad Medani, Sudan)

Charles Ashby (St. John's University, New York, USA)

Xin Cai (Fred Hutchinson Cancer Research Center, Seattle, WA, USA)

Lili Chen (Fox Chase Cancer Center, Philadelphia, PA, USA)

Chao Cheng (Sun Yat-Sen University, Guangzhou, China)

Pingping Chen (University of Miami, Miami, FL, USA)

Wen Deng (College of Pharmacy and Health Sciences, St. John's University, NY, USA)

Rui Ding (Rutgers University Cancer Institute of New Jersey)

Zhiyong Ding (The University of Texas MD Anderson Cancer Center)

Doudou (Irs) Fan (Frontage laboratories, PA, USA)

Simona Di Francesco (G. D'Annunzio University of Chieti, Chieti, Itlay)

Amal Kaddoumi (The University of Louisiana, Monroe, LA, USA)

Aihua Li (Epitomics Inc., Burlingame, USA)

Nan Li (National Cancer Institute, NIH, Bethesda, MD, USA)

Xing-Jie Liang (National Center for Nanoscience and Technology of China, Beijing, China)

Jui-Teng Lin  (New Vision Inc. Taiwan)

Tianxin Lin (Sun Yat-Sen University, Guangzhou, China)

Yong-Yu Liu (University of Louisiana, Monroe, USA)

Jiachun Lu (Guangzhou Medical University, Guangzhou, China)

Yong-Jie Lu (Queen Mary University of London, London, UK)

Bashir A. Lwaleed (Southampton General Hospital, Southampton, UK)

Linghua Meng (Shanghai Institute of Materia Medica, Shanghai, China)

J. V. Pergolizzi Jr. (Johns Hopkins University School of Medicine, Baltimore, MD, USA)

Haili Qian (Chinese Academy of Medical Sciences, Beijing, China)

Tong Shen (Mount Sinai Medical Center, New York, NY, USA)

Suneet Shukla (National Cancer Institute, Bethesda, USA)

Qiusheng Si (Mount Sinai School of Medicine, New York, NY, USA)

Gui Su (University of Wisconsin-Madison, Madison, WI, USA)

Tanaji Talele (St.John's University, New York, NY, USA)

Robert Taylor Jr. (NEMA Research Inc., Naples, FL, USA)

Yin Wang (The George Washington University School of Medicine and Health Sciences, Washington, DC, USA)

Yi-Jun Wang (University of Pittsburgh Cancer Institute, USA)

Zhiqiang Wang (The University of Miami, Miami, FL, USA)

Imtiaz Ahmed Wani (District Hospital, Bandipore, India)

Chung-Pu Wu (Chang Gung University, Tao-Yuan, Taiwan)

Tao Xu (First People's Hospital of Foshan Affiliated to Sun Yat-sen University, Foshan, China)

Yong Xue (University of California, Los Angeles, CA, USA)

Dong-Hua Yang (Fox Chase Cancer Center, Philadelphia, USA)

Lu Yang (Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA)

Dongmei Zhang (Jinan University College of Pharmacy, Guangzhou, China)

Xingcai (Michael) Zhang (Cambridge, MA & Houston, TX)

Jian-ye Zhang (Guangzhou Medical University, China)

Hua Zhu (The Ohio State University, Ohio, OH, USA)

Francesco Ziglioli (University-Hospital of Parma, Parma, Italy)

 Reviewers :

Aihua Li (USA) Akira Yamada (Japan) Amal Kaddoumi (USA) Amit K Tiwari (USA) Atish Patel (USA) Baoxiong Zhuang (China) Bo Pei (USA) Chao Cheng (China) Charles R. Ashby Jr. (USA) Chunpu Wu (Taipei, China) Deshen Wang (USA) Dong-Hua Yang (USA) Dongmei Zhang (China) Fang Wang (China) Fanlin Kong (USA) Francesco Ziglioli (USA) Gary A Piazza (USA) Gui Su (USA) Hao Zeng (USA) Hardik Patel (USA) Hiroshi Nakagawa (Japan) Holly Kuang (China) Hong May Sim (USA) Hua Zhu (USA) Hui Zhang (USA) Imtiaz Wani (India) Jiangyong Ouyang (USA) Jing Li (China)

Jinxuan Pan (China) John Chen (Hongkong, China) Jonathan Sheps (Canada) Jun Xie (China) Kamlesh Sodani (USA) Keiko Takatori (Japan) Khalid El Sayed (USA) Khyati Kapoor (USA) King-Leung Fung (USA) Linhua Meng (China) Liwu Fu (China) Marc Symons (USA) Md Tozamme Hoque (Canada) Michael Zhang (USA) Olorunseun Ogunwobi (USA) Peorong Ding (China) Pin Lan (China) Priyank Kumar (USA) Qi Li (China) Qiao-Hong Duan (USA) Qinqing Cai (China) Qiusheng Si (USA) Renxue Wang (Canada) Robert Taylor Jr. (USA) Rong Xiao (China) Ruihua Xu (China) S. Khan (USA) Shuang Chen (China)

Shuji Kojima (Japan) Shuzhen Chen (China) Simona Di Francesco (Italy) Suneet Shukla (USA) Tanaji Talele (USA) Tao Xu (China) Tatsuhiko Furukawa (Japan) Tianxin Lin (China) Wei Jin (China) Wei Zhu (China) Wen Deng (USA) Xiang-Hong Peng (USA) Xiaocong Huang (Astralia) Xiaoming Xie (China) Xin Cai (USA) Xing-Xiang Peng (USA) Yangzhong Liu (China) Yihang Pan (USA) Yingtai Chen (China) Yong Xue (USA) Yongsu Zhen (China) Yongyu Liu (USA) Yuchun Luo (USA) Yue-Li Sun (China) Zhaoqian Liu (China) Zhi Shi (China) Zhihong Yang (USA)

 

Jian-ye Zhang

The below articles have been selected by the  Editor in Chief to be the top articles published in the journal. The topic, scientific quality and importance in the field where collectively considered while making this selection Vol. 5, No. 4 Vol. 5, No. 3 Vol. 5, No. 2 Vol. 5, No. 1 Vol. 4, No. 4 Vol. 4, No. 3 Vol. 4, No. 2 Vol. 4, No. 1 Vol. 3, No. 4 Vol. 3, No. 3 Vol. 3, No. 2 Vol. 3, No. 1 Vol. 2, No. 4 Vol. 2, No. 3 Vol. 2, No. 2 Vol. 2, No. 1

Volume 5, Number 4

Volume 5, Number 3

Recent Advances in Understanding the Structure and Function Relationship of Multidrug Resistance-Linked ABC Transporter P-glycoprotein - Pages 88-98 Fei Zhou, Lothar Esser and Di Xia DOI: http://dx.doi.org/10.6000/1929-2279.2016.05.03.2

Volume 5, Number 2

Establishment and Characterization of Primary Human Ovarian Cancer Stem Cell Line (CD44+ve) - Pages 59-66 Amoura Abouelnaga, Ghada A. Mutawa, Hassan Abdelghaffar, Mohamed Sobh, Sahar Hamed and Shaker A. Mousa DOI: http://dx.doi.org/10.6000/1929-2279.2016.05.02.3

Volume 5, Number 1

Volume 4, Number 4

The Role of Exosomes and its Cargos in Drug Resistance of Cancer - Pages 179-187 Yujie Xie and Liwu Fu DOI: http://dx.doi.org/10.6000/1929-2279.2015.04.04.6

Volume 4, Number 3

Human Chorionic Gonadotropin (hCG) Testing in Specimens of Tumor and Myometrial Tissues During Surgical Treatment of Gestational Trophoblastic Tumors - Pages 122-126 Reda Hemida, Mohammad Arafa, Hosam AbdElfattah and Doaa Sharaf-Eldin DOI: http://dx.doi.org/10.6000/1929-2279.2015.04.03.3

Volume 4, Number 2

Antioxidant and Anticancer Activities of Raspberry Extracts - Pages 54-59 You-Qiu Xue, Ke-Jun Cheng, Jian-Ge Qiu, Xiao-Long Mei, Wen-Ji Zhang, Qi-Wei Jiang, Wu-Ming Qin, Yang Yang, Di-Wei Zheng, Yao Chen, Meng-Ning Wei, Dong-Mei Huo, Xing Wei and Zhi Shi DOI: http://dx.doi.org/10.6000/1929-2279.2015.04.02.2

Volume 4, Number 1

Obesity and Breast Cancer: Molecular and Epidemiological Evidence - Pages 30-42 Nehad M. Ayoub and Amal Kaddoumi DOI: http://dx.doi.org/10.6000/1929-2279.2015.04.01.3

Volume 3, Number 4

The Polymorphism of EME1 Gene is Associated with an Increased Risk of Lung Cancer: A Case-Control Study from Chinese Population - Pages 174-181 Jianwei Zhao, Yongxiu Chen, Xiaoxiao Lu, Di Wu, Jiansong Chen, Zhihuang Chen, Lin Liu, Lei Yang, Lan Zhang, Yifeng Zhou and Jiachun Lu DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.04.1 Oxycodone Immediate Release for Cancer Pain Management in Turkey: Maximizing Value in Opioid Analgesics - Pages 207-217 Joseph V. Pergolizzi Jr., Robert Taylor Jr., Gianpietro Zampogna, Fuat H. Demirelli, Serdar Erdine and Robert B. Raffa DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.04.5 The Association of Genetic Polymorphisms of TNFα, TNF-R1, and TNF-R2 and Lung Cancer Chemotherapy Response - Pages 218-225 Yi Zheng, Ji-Ye Yin, Ying Wang, Xiang-Ping Li, Juan Chen, Chen-Yue Qian, Xiao-Ke Wen, Wei Zhang, Hong-Hao Zhou and Zhao-Qian Liu DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.04.6

Volume 3, Number 3

Surface Functionalization of Gold Nanoparticles for Simultaneous Suppression of Cancer Stem Cells and Cancer Cells - Pages 123-128 Yujiro Naruse DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.03.1 Patterns of Distant Failure and Second Primary Cancers in Patients with Oropharyngeal Squamous Cell Carcinoma: Implications for Surveillance Methodology - Pages 151-161 Edwin F. Crandley, David D. Wilson, Austin J. Sim, Neil Majithia, Edward B. Stelow, Mark J. Jameson, David C. Shonka Jr., Asal S. Rahimi and Paul W. Read DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.03.5 Sildenafil Enhances the Anticancer Activity of Paclitaxel in an ABCB1-Mediated Multidrug Resistance Xenograft Mouse Model - Pages 169-173 Kamlesh Sodani, Amit K. Tiwari, Chun-Ling Dai, Alaa H. Abuznait, Atish Patel, Zhi-Jie Xiao, Charles R. Ashby, Amal Kaddoumi, Li-Wu Fu and Zhe-Sheng Chen DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.03.7

Volume 3, Number 2

NACA (Nascent-Polypeptide-Associated Complex α Subunit) Against Apoptosis in B Lymphoma Cell is Independent of β Subunit (NACB) - Pages 85-92 Weiqi Zeng, Min Qi, Jianglin Zhang and Xiang Chen DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.02.1 Case Report: Coexistence of Non-Keratinizing Squamous Cell Carcinoma and Follicular Lymphoma in Nasopharynx - Pages 93-96 Tao Xu, Weihong Wei, Zeli Huang and Weihan Hu DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.02.2 The Overexpression of ABCG2 Reduces the Efficacy of Volasertib (BI 6727) and GSK641364 in Human S1-M1-80 Colon Carcinoma Cells - Pages 108-116 Sung-Han Hsiao, Shi-Yu Luo, Ching-Ya Su, Wei-Cherng Tuo, Cheng-Ting Chiang, Yan-Qing Li, Yang-Hui Huang and Chung-Pu Wu DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.02.5

Volume 3, Number 1

EGCG Suppresses Melanoma Tumor Angiogenesis and Growth without Affecting Angiogenesis and VEGF Expression in the Heart and Skeletal Muscles in Mice - Pages 19-29 Kevan B. Tucker, Kristina L. Makey, Edmund Chinchar, Min Huang, Natale Sheehan, Srinivasan Vijayakumar and Jian-Wei Gu DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.01.3 Factors Influencing Percentage Yield of Side Population Isolated in Ovarian Cancer Cell Line SK-OV-3 - Pages 42-58 Yuling Chen, Sui-Lin Mo, Felix Wu Shun Wong, George Qian Li, Yen Siew Loh, Basil D. Roufogalis, Maureen V. Boost and Daniel Man-Yuen Sze DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.01.5 B5H7, a Morpholine Derivative of 23-Hydroxybetulinic Acid, Reverses Doxorubicin Resistance in HepG2/ADM - Pages 59-66 Nan Yao, Dao-Lu Liu, Ying-Jie Li, Zhe-Sheng Chen, Zhi Shi, Wei-Min Chen, Zhe Yao, Dong-Mei Zhang and Wen-Cai Ye DOI: http://dx.doi.org/10.6000/1929-2279.2014.03.01.6

Volume 2, Number 4

Disease–Free Remission Exceeding 37 Years in Patients Treated as Children for Acute Leukemia (AL) with Immunotherapy Using Viable (Cryopreserved) Allogeneic Leukemic Cells - Pages 254-264 Tatiana I. Bulycheva, Svetlana A. Mayakova and Simon V. Skurkovich DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.04.4 Is the Neoadjuvant Docetaxel, Cisplatin and 5-Fluorouracil Regimen Superior to Classic Cisplatin and 5-Fluorouracil for Locoregionally Advanced Nasopharyngeal Carcinoma? - Pages 297-305 Zeli Huang, Jiezhan Feng, Shaoen Li, Weihong Wei, Guoyi Zhang, Qiuxia Lu, Yongfeng Wu, Li Lin and Tao Xu DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.04.8 Vemurafenib (PLX4032, Zelboraf®), a BRAF Inhibitor, Modulates ABCB1-, ABCG2-, and ABCC10-Mediated Multidrug Resistance - Pages 306-317 Saurabh G. Vispute, Jun-Jiang Chen, Yue-Li Sun, Kamlesh S. Sodani, Satyakam Singh, Yihang Pan, Tanaji Talele, Charles R. Ashby Jr and Zhe-Sheng Chen DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.04.9

Volume 2, Number 3

Cancer Stem Cells: A Review of the Literature and the Implications in Head and Neck Cancer - Pages 186-193 Brianna N. Harris and Uttam K. Sinha DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.03.4 TRAP1 is Involved in Cell Cycle Regulated by Retinoblastoma Susceptibility Gene (RB1) in Early Hypoxia and has Variable Expression Patterns in Human Tumors - Pages 194-210 Jiangting Hu, Ern Yu Tan, Leticia Campo, Russell Leek, Zainina Seman, Helen Turley, Domenico Delia, Alfredo Cesario, Kevin Gatter and Francesco Pezzella DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.03.5 Molecular Genetic Study of the Allelic State of the Cell Cycle Genes (TP53, BRCA1) and Features of the Regulation of the Cytokine Cascade in Breast Cancer - Pages 211-219 S.K. Gantsev, V.Y. Gorbunova, G.F. Galikeeva, E.V. Vorobyeva, E.M. Vasilyeva and R.A. Rustamhanov DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.03.6

Volume 2, Number 2

Potential Solutions in Radiation Hormesis - Pages 95-98 Masao Takatori, Makoto Yagi and Sadao Hattori DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.02.2 The Many Aspects of Off-Label Prescribing in Oncology - Pages 110-115 Anna Gu and Albert I. Wertheimer DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.02.5 Dietary Ascorbic Acid-Mediated Augmentation of Antitumor Activity and Protection Against Toxicities Induced by Cis-Diamminedichloroplatinum-(II) in Dalton’s Lymphoma-Bearing Mice - Pages 116-130 Amenla, Akalesh Kumar Verma and Surya Bali Prasad DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.02.6

Volume 2, Number 1

An Audit to Evaluate the Clinical Safety and PSA Response of Firmagon® (Degarelix) in Patients with Advanced Metastatic Prostate Cancer - Pages 21-25 Nikhil Vasdev, Patricia McClurey, Debra Gray, Aftab Bhatti and David Chadwick DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.01.4 Targeting Cancer Stem Cells with Defined Compounds and Drugs - Pages 36-67 Cord Naujokat and Stefan Laufer DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.01.7 The Reciprocal Interaction of Small Molecule Protein Kinase Inhibitors and ATP-Binding Cassette Transporters in Targeted Cancer Therapy - Pages 68-86 Hong-Ye Zhao, Hongjiang Wei and Xin Wang DOI: http://dx.doi.org/10.6000/1929-2279.2013.02.01.8