Table of Contents
Volume 7 No. 2, 2011
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Long-Term Administration of HMG-COA-Reductase Inhibitor (Simvastatin) affects Brain Serotonin Neurotransmission in Male Rats Sadia Saleem, Saida Haider, Fizza Naqvi, Saiqa Tabassum and Darakhshan J. Haleem DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.01 |
Enhancement of Memory by Lithium in Animal Model of Stress Tahira Perveen, Zehra Batool, Saida Haider and Darakhshan J Haleem DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.02 |
Chemistry |
Determination of Some Toxic and Essential Trace Metals in Some Medicinal and Edible Plants of Karachi City Mahwash Zahra Kirmani, Sheikh Mohiuddin, Farah Naz, Iftikhar Imam Naqvi and Erum Zahir DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.03 |
Two New Diarylesters from Ipomoea Cairica Sumayya Saied, Farhana Batool and Shaista Naz DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.04 |
Geography |
The South Asiatic Monsoon and Flood Hazards in the Indus River Basin, Pakistan Shamshad Akhtar DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.05 |
Mathematics |
Direct-Global and Reverse-Global Aspects of Town-wise Distribution of Karachi Katchi-Abadies Shaheen Abbas and Muhammad Rashid Kamal Ansari DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.06 |
Pharmacology |
Effect of Wet Cupping Therapy on Virulent Cellulitis Secondary to Honey Bee Sting – A Case Report |
Asif Ahmed, Rafeeq Alam Khan, Amjad Ahsan Ali and M. Ahmed Mesaik DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.07 |
Studies of Ketoprofen Toxicity in Avian Species Asif Farooq Awan, Taha Nazir, Muhammad Ashraf, Owais Umer and Habib Ur Rehman DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.08 |
The Effect of Cedrus deodara Root Oil on the Histopathology of Rat Stomach Ijaz Hussain Zaidi, Syed Naeemul Hasan Naqvi, Qamar Aziz, R.M. Tariq, Aneela Qureshi, Mazhar Hussain Hijazi, Muhammed Ahmed Azmi, Shabih Zehra and Rehana Parveen DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.09 |
Physics |
Design and Construction of Very Low Frequency Antenna M. Waheed-uz-Zaman and M.A.K. Yousufzai DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.10 |
Total Global and Diffuse Solar Radiation for Upper Sindh, Pakistan M. Akhlaque Ahmed, Firoz Ahmad and M. Wasim Akhtar DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.11 |
Utilization of Markov Chain Technique to Generate High-Density Wind Speed Data for the Coastal Belt of Pakistan Zeeshan Alam Nayyar, Nayyer Alam Zaigham and Abdul Qadeer DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.12 |
Zoology |
Adverse Effect of Lead Acetate on Drosophila melanogaster Rizwanual Haq, M. Farhanullah Khan and Ehteshamul Haq DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.13 |
Correlation between Body Weight & Egg Weight of Dokki and Fayoumi Hen in Pakistan Rizwanual Haq, Ehteshamul Haq and M. Farhanullah Khan DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.14 |
Determination of LC50 of Chlorpyrifos and Neem Extract on third Instar Larvae of House Flies and their Effect on Fecundity Islam Dad, Masarrat Jahan Yousuf and Syed Ishtiaq Anjum DOI: http://dx.doi.org/10.6000/1927-5129.2011.07.02.15 |
Tahira Perveen*, Zehra Batool, Saida Haider and Darakhshan J Haleem |
ABSTRACT |
Numerous studies have consistently shown that repeated restraint stress produces functional neuromorphological and physiological alteration that are linked to the pathophysiology of brain disorder, like depression and bipolar disorder, causes alteration in cognition and learning memory. Lithium is the drug of choice in the treatment of depression and mania in bipolar disorder as a mood-stabilizing agent. Present study was designed to investigate the effects of long term lithium administration on memory function and its relation with 5-HT metabolism following repeated restraint stress. In this experiment memory was assessed by novel object recognition task in water treated and lithium treated unrestraint and restraint rats. Recognition memory decreased in water treated repeated restraint rats while in lithium treated repeated restraint rats recognition memory increased. 5- HIAA level increased in water treated restraint rats while decreased in lithium treated restraint rats. The findings indicate a role of brain serotonin in improved memory function in repeated restraint rats following long term lithium administration. |
Keywords: Stress, lithium, memory, 5-HIAA. |
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Asif Farooq Awan, Taha Nazir*, Muhammad Ashraf, Owais Umer and Habib Ur Rehman |
ABSTRACT |
Certain environmental factors are very important to stabilize the wild life; avian diseases, vulture crises and ecological annoyance. This should be fixed scientifically to minimize the health hazards. Thus; we have aimed this project to evaluate effects of toxic dosage levels of Ketoprofen in broiler chickens. Two hundred and twenty five (225) healthy broiler chickens were reared upto 28 days and divided into five groups 25 birds in each group. On day 29th four groups were medicated twice a day at dose rate of 50 mg/kg body weight respectively intra-muscularly for four days. Feed and water were provided ad libitum. A physical examination, toxicity and mortality rate were recorded daily. Blood samples was drawn to determination the serum values of Aspartate Transaminase (AST), Alanine Transaminase (ALT), Uric Acid, Alkaline phosphatase (ALP), and Creatinine. Postmortem performed on day 41 after all samples taken. In second experiment other 100 birds were divided into five groups comprising of 20 birds in each group. One of the groups was injected I/M Ketoprofen 5mg/kg twice a day. Postmortem performed after medication on 5th day. Based on the necropsy findings and biochemical analysis it was found that Ketoprofen was not safe drug in the avian species. Keeping in view the environmental problem (vultures crises) it is recommended that Ketoprofen which has good pharmacological effects in human medicine should be avoided in veterinary practice. |
Keywords: Ketoprofen toxicity, Broiler birds, LFT’s |
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M. Waheed-uz-Zaman* and M.A.K. Yousufzai, |
ABSTRACT |
Communication with submerged submarines requires specific techniques and devices which gives totally different criteria as compared to the air. In the ocean salts water provide a hindrance for electromagnetic radiation such as normal radio communication because sat water acts as thick conductors. It is the normal practice in submarine is to surface and raise an antenna above the water surface to use standard technology. In case of nuclear-powered submarines it is very difficult to come on surface for communication. A thorough research it was analyzed by the scientists that VLF radio waves (3-30 KHz) can penetrate sea water down to a depth of roughly 20 meters. It’s really a backup of existing, higherfrequency, radio-based communication systems. Moreover the rate of information and speed of transmission of other systems, it “gets through” while the others cannot. Previously it was a one-way, non-voice system, but it provides sufficient information to the submarine’s commander to surface to receive more information via other means but in this paper a view is given to the readers the both way communication under water with submarines. This is an experimental effort to enquire the live data and with the passage of time and effort it can be used for both way communications between two submarines. |
Keywords: VLF antenna, propagation in sea water, radio waves communication, nuclear submarine. |
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Rizwanual Haq, M. Farhanullah Khan and Ehteshamul Haq |
ABSTRACT |
As lead is an important environmental noxious waste which directly or indirectly contaminate the foods, soil water, and air thus, insects could be influenced easily by the lead. Therefore, lead was studied as lead acetate in different doses. viz 0.125 mg., 0.25 mg., 0.5 mg, 01 mg and 02 mg, on external morphology on Drosophila melanogaster at 48 hours post treatment. It was observed that under the effects of lead abnormalities and deformity were developed in the larvae of flies. Morphological changes were observed as elongated wings, de-shaped wings, elongated and folded legs, change in color of larvae, pupae and adults. Some other structural abnormalities of larvae and pupa shape were also observed. Thus the Dipterous flies could present a useful module for the quick transmission of the environmental hazards due to lead contamination, which exerts a specific physiological and morphological effect on these flies. So, in this respect, Drosophila melanogaster, could be used as a test method for heavy metals effects. |
Keywords: Heavy metal, lead acetate, D. melanogaster. |
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