A Prospective Study on the Application of Endometrial Cytology Examination in the Screening of Endometrial Cancer
Pages 85-89
Zheng Fang, Du Lianfang, Xie Cuiqi, Shao Shaowei, Luo Qiaoming, Li Qiyan and Ma Ling

DOI: http://dx.doi.org/10.6000/1929-2279.2015.04.02.6

Published: 07 May 2015

Abstract: Background: Endometrial cancer is one of the most common gynecology malignancies. But there is still lack of an accurate, reliable, convenient, easy, economical and practical method for early detection of endometrial cancer and precancerous lesions. The aim of this study is to evaluate the specimen quality and diagnostic accuracy of endometrial cytology examination in the screening of endometrial cancer.

Methods: 95 patients with abnormal uterine bleeding or vaginal ultrasound examination results indicating intrauterine abnormalities and needing endometrial examination were investigated, and specimens were collected using endometrial sampling device for cytology (ESDC) and sliced using thinprep cytology test (TCT), meanwhile, hysteroscopy auxiliary diagnostic curettage and histopathological examination were performed.

Results: The satisfaction rate was 100% for the specimens collected using ESDC and 97.9% for those using diagnostic curettage. The difference in the satisfaction rate of collecting specimens was statistically significant between the two methods, and the satisfaction rate of collecting specimen using endometrial cytology was superior to that using diagnostic curettage. Taking diagnostic curettage histopathologic results as "gold standard", the sensitivity of endometrial cytology was 63.6%, specificity 93.6%, positive predictive value 70% and negative predictive value 95.2% in the screening of endometrial cancer.

Conclusion: Endometrial cytology can be used as a reliable, safe and simple method in the screening of endometrial cancer.

Keywords: Endometrial cytology, endometrial sampling device for cytology, endometrial cancer, thinprep cytology test.

Laparoscopic Adrenal Surgery for Giant Ganglioneuroma
Pages 90-94
Bruno Costa do Prado, Marcelo Cabral Lamy de Miranda, Marcio Maia Lamy de Miranda and Anibal Wood Branco

DOI: http://dx.doi.org/10.6000/1929-2279.2015.04.02.7

Published: 07 May 2015

Abstract: We present herein a case of a 24-year-old woman with incidentally diagnosed right adrenal ganglioneuroma with 14cm in size that was removed completely by the laparoscopic approach. The patient was asymptomatic and the tumor was first diagnosed on abdominal ultrasonography. A subsequent computed tomography (CT) of the abdomen confirmed a 12x 11x9cm complex expansive mass of right adrenal, with well-defined outlines. Magnetic resonance imaging (MRI) showed a solid lesion measuring 11 x 9 x 11cm arising from the right adrenal. Laparoscopic complete excision of the mass was accomplished through a transabdominal lateral approach. The surgical specimen weighed 665 g and 14 x 10 x 7 cm in size. There was no complication in postoperative period, and the patient was released from the hospital two days after the operation. The patient resumed her normal activities in one week. Histology was consistent with an adrenal ganglioneuroma. A control CT was made one year after the surgery with no evidence of lesion suggestive of relapse. Adrenal ganglioneuromas are rare lesions with a benign behavior in which surgery is the only possible form of treatment. In centers of advanced laparoscopy this method of access can be used, even for larger lesions.

Keywords: Urology, Oncological Surgery, general laparoscopy.